{"description":"Documents matching 'bulk drug substances', published on or after 07/23/2026, and from Food and Drug Administration","count":1,"total_pages":1,"results":[{"title":"Substances Generally Recognized as Safe","type":"Proposed Rule","abstract":"The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).","document_number":"2026-16296","html_url":"https://www.federalregister.gov/documents/2026/08/11/2026-16296/substances-generally-recognized-as-safe","pdf_url":"https://www.govinfo.gov/content/pkg/FR-2026-08-11/pdf/2026-16296.pdf","public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2026-16296.pdf?1786374907","publication_date":"2026-08-11","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"excerpts":"notices for the use of a human or animal food <span class=\"match\">substance</span> that is purported to be GRAS under the conditions of its intended use under section 201(s) of the FD&amp;C Act (21 U.S.C. 321(s))\n . \n Food <span class=\"match\">substances</span> include both ingredients and <span class=\"match\">substances</span> added indirectly, such as from food packaging. The proposed rule would require any person introducing a <span class=\"match\">substance</span> into interstate commerce under the GRAS provision of section 201(s) of the FD&amp;C Act to notify FDA of the basis for their conclusion that the <span class=\"match\">substance</span> is GRAS under the conditions of its intended"}]}