{"abstract":"The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by Merial Ltd. The supplemental NADA provides for changes to labeling of ivermectin sustained-release bolus for cattle.","action":"Final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2000/07/26/00-18827.html","cfr_references":[{"chapter":null,"citation_url":null,"part":520,"title":21}],"citation":"65 FR 45876","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective July 26, 2000.","disposition_notes":null,"docket_ids":[],"dockets":[],"document_number":"00-18827","effective_on":"2000-07-26","end_page":45876,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2000/07/26/00-18827.xml","html_url":"https://www.federalregister.gov/documents/2000/07/26/00-18827/oral-dosage-form-new-animal-drugs-ivermectin-sustained-release-bolus","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/00-18827?publication_date=2000-07-26","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2000-07-26/00-18827/mods.xml","not_received_for_publication":null,"page_length":1,"page_views":{"count":44,"last_updated":"2026-04-04 12:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2000-07-26/pdf/00-18827.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2000-07-26","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2000/07/26/00-18827.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":45876,"subtype":null,"title":"Oral Dosage Form New Animal Drugs; Ivermectin Sustained-Release Bolus","toc_doc":"Ivermectin sustained-release bolus","toc_subject":"Animal drugs, feeds, and related products:","topics":["Animal drugs"],"type":"Rule","volume":65}