{"abstract":"The Food and Drug Administration (FDA) is authorizing the use, on food labels and in food labeling, of health claims on the association between plant sterol/stanol esters and reduced risk of coronary heart disease (CHD). FDA is taking this action in response to a petition filed by Lipton (plant sterol esters petitioner) and a petition filed by McNeil Consumer Healthcare (plant stanol esters petitioner). Based on the totality of publicly available evidence, the agency has concluded that plant sterol/stanol esters may reduce the risk of CHD.","action":"Interim final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2000/09/08/00-22892.html","cfr_references":[{"chapter":null,"citation_url":null,"part":101,"title":21}],"citation":"65 FR 54686","comment_url":null,"comments_close_on":"2000-09-08","correction_of":null,"corrections":[],"dates":"This rule is effective September 8, 2000. Submit written comments by November 22, 2000. The Director of the Office of the Federal Register approves the incorporation by reference in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 of certain publications in 21 CFR 101.83(c)(2)(ii)(A)(2) and (c)(2)(ii)(B)(2), as of September 8, 2000.","disposition_notes":null,"docket_ids":["Docket Nos. 00P-1275 and 00P-1276"],"dockets":[],"document_number":"00-22892","effective_on":"2000-09-08","end_page":54739,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2000/09/08/00-22892.xml","html_url":"https://www.federalregister.gov/documents/2000/09/08/00-22892/food-labeling-health-claims-plant-sterolstanol-esters-and-coronary-heart-disease","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/00-22892?publication_date=2000-09-08","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2000-09-08/00-22892/mods.xml","not_received_for_publication":null,"page_length":54,"page_views":{"count":2059,"last_updated":"2026-10-23 08:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2000-09-08/pdf/00-22892.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2000-09-08","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2000/09/08/00-22892.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":54686,"subtype":null,"title":"Food Labeling: Health Claims; Plant Sterol/Stanol Esters and Coronary Heart Disease","toc_doc":"Plant sterol/stanol esters and coronary heart disease; health claims","toc_subject":"Food for human consumption:","topics":["Food labeling","Incorporation by reference","Nutrition","Reporting and recordkeeping requirements"],"type":"Rule","volume":65}