{"abstract":"The Food and Drug Administration (FDA) is announcing its determination that CHYMODIACTIN (chymopapain 10,000 units/vial injection) was not withdrawn from sale for reasons of safety or effectiveness. This determination will allow FDA to approve abbreviated new drug applications (ANDAs) for chymopapain 10,000 units/vial injection.","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2003/01/27/03-1742.html","cfr_references":[],"citation":"68 FR 3886","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":null,"disposition_notes":null,"docket_ids":["Docket No. 02P-0068"],"dockets":[],"document_number":"03-1742","effective_on":null,"end_page":3887,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2003/01/27/03-1742.xml","html_url":"https://www.federalregister.gov/documents/2003/01/27/03-1742/determination-that-chymopapain-10000-unitsvial-injection-was-not-withdrawn-from-sale-for-reasons-of","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/03-1742?publication_date=2003-01-27","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2003-01-27/03-1742/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":578,"last_updated":"2026-04-28 10:15:06 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2003-01-27/pdf/03-1742.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2003-01-27","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2003/01/27/03-1742.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":3886,"subtype":null,"title":"Determination That Chymopapain 10,000 Units/Vial Injection Was Not Withdrawn From Sale for Reasons of Safety or Effectiveness","toc_doc":"CHYMODIACTIN","toc_subject":"Human drugs:","topics":[],"type":"Notice","volume":68}