{"abstract":"EPA is taking direct final action to explicitly ban research for pesticides involving intentional exposure of human subjects who are nursing women, and therefore providing protection to any nursing infants who may also be exposed. The direct final rule also prohibits EPA reliance in actions under the pesticide laws on research involving intentional exposure of nursing women.","action":"Direct final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2006/06/23/06-5649.html","cfr_references":[{"chapter":null,"citation_url":null,"part":26,"title":40}],"citation":"71 FR 36172","comment_url":null,"comments_close_on":"2006-07-24","correction_of":null,"corrections":[],"dates":"This direct final rule is effective on August 22, 2006 without further notice, unless EPA receives adverse comment on or before July 24, 2006. If EPA receives adverse comments to the direct final rule, EPA will publish a timely withdrawal document in the Federal Register informing the public that this direct final rule rule will not take effect.","disposition_notes":null,"docket_ids":["EPA-HQ-OPP-2003-0132","FRL-8071-6"],"dockets":[],"document_number":"06-5649","effective_on":"2006-08-22","end_page":36176,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2006/06/23/06-5649.xml","html_url":"https://www.federalregister.gov/documents/2006/06/23/06-5649/protections-for-subjects-in-human-research-nursing-women","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/06-5649?publication_date=2006-06-23","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2006-06-23/06-5649/mods.xml","not_received_for_publication":null,"page_length":5,"page_views":{"count":67,"last_updated":"2026-04-04 12:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2006-06-23/pdf/06-5649.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2006-06-23","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2006/06/23/06-5649.txt","regulation_id_number_info":{"2070-AD57":{"issue":"200304","html_url":"https://www.federalregister.gov/regulations/2070-AD57/acceptability-of-research-using-human-subjects","title":"Acceptability of Research Using Human Subjects","xml_url":"http://www.reginfo.gov/public/do/eAgendaViewRule?pubId=200304&RIN=2070-AD57&operation=OPERATION_EXPORT_XML","priority_category":"Other Significant"}},"regulation_id_numbers":["2070-AD57"],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-11-12T19:40:33Z"},"regulations_dot_gov_url":null,"significant":true,"signing_date":null,"start_page":36172,"subtype":null,"title":"Protections for Subjects in Human Research; Nursing Women","toc_doc":"Nursing women and nursing infants; additional protections","toc_subject":"Protection of human subjects:","topics":[],"type":"Rule","volume":71}