{"abstract":"EPA is promulgating significant new use rules (SNURs) under section 5(a)(2) of the Toxic Substances Control Act (TSCA) for 15 chemical substances which were the subject of premanufacture notices (PMNs). Three of these chemical substances are subject to TSCA section 5(e) consent orders issued by EPA. This action requires persons who intend to manufacture, import, or process any of these 15 chemical substances for an activity that is designated as a significant new use by this rule to notify EPA at least 90 days before commencing that activity. The required notification will provide EPA with the opportunity to evaluate the intended use and, if necessary, to prohibit or limit that activity before it occurs.","action":"Direct final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2010/02/01/2010-1936.html","cfr_references":[{"chapter":null,"citation_url":null,"part":9,"title":40},{"chapter":null,"citation_url":null,"part":721,"title":40}],"citation":"75 FR 4983","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"The effective date of this rule is April 2, 2010 without further notice, unless EPA receives written adverse or critical comments, or notice of intent to submit adverse or critical comments before March 3, 2010. This rule shall be promulgated for purposes of judicial review at 1 p.m. (e.s.t.) on February 16, 2010.","disposition_notes":null,"docket_ids":["EPA-HQ-OPPT-2008-0918","FRL-8438-4"],"dockets":[],"document_number":"2010-1936","effective_on":"2010-04-02","end_page":4996,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2010/02/01/2010-1936.xml","html_url":"https://www.federalregister.gov/documents/2010/02/01/2010-1936/significant-new-use-rules-on-certain-chemical-substances","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2010-1936?publication_date=2010-02-01","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2010-02-01/2010-1936/mods.xml","not_received_for_publication":null,"page_length":14,"page_views":{"count":352,"last_updated":"2026-04-04 16:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2010-02-01/pdf/2010-1936.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2010-02-01","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2010/02/01/2010-1936.txt","regulation_id_number_info":{"2070-AB27":{"issue":"201404","html_url":"https://www.federalregister.gov/regulations/2070-AB27/significant-new-use-rule-snur-chemical-specific-snurs-to-extend-provisions-of-section-5-e-orders","title":"Significant New Use Rule (SNUR); Chemical-Specific SNURs To Extend Provisions of Section 5(e) Orders","xml_url":"http://www.reginfo.gov/public/do/eAgendaViewRule?pubId=201404&RIN=2070-AB27&operation=OPERATION_EXPORT_XML","priority_category":"Routine and Frequent"}},"regulation_id_numbers":["2070-AB27"],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Honeywell AC Study: \"Refrigerant Exposure to Service Personnel or DIYers Due to Leakage of 12 oz Charging Cans\"","document_id":"EPA-HQ-OPPT-2008-0918-0104"},{"title":"Monitoring Date for Honeywell Study on HFO-1234yf","document_id":"EPA-HQ-OPPT-2008-0918-0103"},{"title":"Honeywell International Compliance with Good Laboratory Practices","document_id":"EPA-HQ-OPPT-2008-0918-0102"},{"title":"Risk Assessment of Single Exposures to HFO-1234yf (P07-0601)","document_id":"EPA-HQ-OPPT-2008-0918-0101"},{"title":"EPA Review of HFO-1234yf: A 2-Phase Inhalation Screening Study and Single Exposure Study in Rabbits via Whole-Body Inhalation Exposure (GLP)","document_id":"EPA-HQ-OPPT-2008-0918-0100"},{"title":"HFO-1234yf: A 2-Phase Inhalation Screening Study and Single Exposure Study in Rabbits via Whole-Body Inhalation Exposure (GLP)","document_id":"EPA-HQ-OPPT-2008-0918-0099"},{"title":"USEPA Email Response to February 6, 2010 Letter: Data Needs to Assess SNAP and SNUR HFO-1234yf","document_id":"EPA-HQ-OPPT-2008-0918-0097"},{"title":"Honeywell Response to USEPA Questions on Submitted Exposure Study","document_id":"EPA-HQ-OPPT-2008-0918-0096"},{"title":"USEPA Questions to Honeywell on Submitted Exposure Study","document_id":"EPA-HQ-OPPT-2008-0918-0095"},{"title":"Appendix G: Technical Support Document Staff Analysis on Emissions and Economic Impact of Proposed Regulation for Small Containers of Automotive Refrigerant","document_id":"EPA-HQ-OPPT-2008-0918-0094"}],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPPT-2008-0918","supporting_documents_count":90,"docket_id":"EPA-HQ-OPPT-2008-0918","regulation_id_number":null,"title":"Significant New Use Rule of Certain Chemical Substances","checked_regulationsdotgov_at":"2010-02-01T16:02:05Z"},"regulations_dot_gov_url":null,"significant":false,"signing_date":null,"start_page":4983,"subtype":null,"title":"Significant New Use Rules on Certain Chemical Substances","toc_doc":"Significant New Use Rules on Certain Chemical Substances","toc_subject":null,"topics":["Chemicals","Environmental protection","Hazardous substances","Reporting and recordkeeping requirements"],"type":"Rule","volume":75}