{"abstract":"The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry and FDA staff entitled \"`Harmful and Potentially Harmful Constituents' in Tobacco Products as Used in Section 904(e) of the Federal Food, Drug, and Cosmetic Act.\" This guidance provides written guidance to industry and FDA staff on certain provisions of the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act).","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2011/01/31/2011-1990.html","cfr_references":[],"citation":"76 FR 5387","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"Submit either electronic or written comments on this guidance at any time.","disposition_notes":null,"docket_ids":["Docket No. FDA-2010-D-0281"],"dockets":[],"document_number":"2011-1990","effective_on":null,"end_page":5388,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2011/01/31/2011-1990.xml","html_url":"https://www.federalregister.gov/documents/2011/01/31/2011-1990/guidance-for-industry-and-food-and-drug-administration-staff-harmful-and-potentially-harmful","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2011-1990?publication_date=2011-01-31","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2011-01-31/2011-1990/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":245,"last_updated":"2026-09-21 16:15:06 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2011-01-31/pdf/2011-1990.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2011-01-31","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2011/01/31/2011-1990.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-02-20T21:19:16Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":5387,"subtype":null,"title":"Guidance for Industry and Food and Drug Administration Staff; “`Harmful and Potentially Harmful Constituents' in Tobacco Products as Used in Section 904(e) of the Federal Food, Drug, and Cosmetic Act”; Availability","toc_doc":"Harmful and Potentially Harmful Constituents in Tobacco Products, etc.","toc_subject":"Guidance for Industry and Food and Drug Administration Staff; Availability:","topics":[],"type":"Notice","volume":76}