{"abstract":"The Food and Drug Administration (FDA) is announcing that Gruma Corporation, Spina Bifida Association, March of Dimes Foundation, American Academy of Pediatrics, Royal DSM N.V., and National Council of La Raza have jointly filed a petition proposing that the food additive regulations be amended to provide for the safe use of folic acid in corn masa flour.","action":"Notice of petition.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2012/06/13/2012-14263.html","cfr_references":[{"chapter":null,"citation_url":null,"part":172,"title":21}],"citation":"77 FR 35317","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":null,"disposition_notes":null,"docket_ids":["Docket No. FDA-2012-F-0480"],"dockets":[],"document_number":"2012-14263","effective_on":null,"end_page":35317,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2012/06/13/2012-14263.xml","html_url":"https://www.federalregister.gov/documents/2012/06/13/2012-14263/gruma-corporation-spina-bifida-association-march-of-dimes-foundation-american-academy-of-pediatrics","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2012-14263?publication_date=2012-06-13","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2012-06-13/2012-14263/mods.xml","not_received_for_publication":null,"page_length":1,"page_views":{"count":236,"last_updated":"2026-10-23 16:15:07 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2012-06-13/pdf/2012-14263.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2012-14263.pdf?1339505606","publication_date":"2012-06-13","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2012/06/13/2012-14263.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Reference 12 Memorandum from J. Zang, Toxicology Team, Division of Petition Review, to J. Kidwell, Division of Petition Review, March 23, 2016 re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0027"},{"title":"Reference 24 The Availability of Food Folate in Man re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0026"},{"title":"Reference 21 The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0025"},{"title":"Reference 20 Cognitive impairment in older Americans in the age of folic acid fortification re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0024"},{"title":"Reference 19 Vital and Health Statistics re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0023"},{"title":"Reference 18 Vitamin B12 deficiency re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0022"},{"title":"Reference 17 Vitamin B12 Deficiency re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0021"},{"title":"Reference 16 Vitamin B12 Deficiency re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic Acid","document_id":"FDA-2012-F-0480-0020"},{"title":"Reference 15 The Prevalence of Low Serum Vitamin B-12 Status in the Absence of Anemia or Macrocytosis Did Not Increase among Older U.S. Adults after Mandatory Folic Acid Fortification re Food Additives Permitted for Direct Addition to Food for Human  Cons","document_id":"FDA-2012-F-0480-0019"},{"title":"Reference 13 Memorandum from H. Lee, Chemistry Review Group, Division of Petition Review, to J. Kidwell, Regulatory Group I, Division of Petition Review, April 2, 2014 re Food Additives Permitted for Direct Addition to Food for Human  Consumption; Folic A","document_id":"FDA-2012-F-0480-0018"}],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=FDA-2012-F-0480","supporting_documents_count":21,"docket_id":"FDA-2012-F-0480","regulation_id_number":null,"title":"Gruma Corporation, Spina Bifida Association, March of Dimes Foundation, American Academy of Pediatrics, Royal DSM N.V., and National Council of La Raza; Filing of Food Additive Petition FAP 2A4796","checked_regulationsdotgov_at":"2012-07-03T08:04:52Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":35317,"subtype":null,"title":"Gruma Corporation, Spina Bifida Association, March of Dimes Foundation, American Academy of Pediatrics, Royal DSM N.V., and National Council of La Raza; Filing of Food Additive Petition","toc_doc":"Gruma Corp., Spina Bifida Association, March of Dimes Foundation, American Academy of Pediatrics, Royal DSM N.V., and National Council of La Raza","toc_subject":"Filing of Food Additive Petitions:","topics":[],"type":"Proposed Rule","volume":77}