{"abstract":"This is notice, in accordance with 35 U.S.C. 209(c)(1) and 37 CFR 404.7(a)(1)(i), that the National Institutes of Health, Department of Health and Human Services, is contemplating the grant of an exclusive evaluation option license to practice the inventions embodied in PCT Patent Application No. PCT/US2009/054478, U.S. Patent Application No. 13/059,335 and foreign equivalents thereof entitled \"Chemopreventive of Head and Neck Squamous Cell Carcinoma\" (HHS Ref. No. E-302-2008/0) and PCT Patent Application No. PCT/IL2010/000694, U.S. Patent Application No. 13/391,756 and foreign equivalents thereof entitled \"Prevention and Treatment of Oral and Lips Diseases Using Sirolimus and Derivatives Sustained Release Delivery Systems for Local Application to the Oral Cavity\" (HHS Ref. No. E-282-2009/0) to Rapamycin Holdings, Inc., which is located in San Antonio, TX. The patent rights in these inventions have been assigned to the United States of America. The prospective exclusive evaluation option license territory may be worldwide and the field of use may be limited to use of the Licensed Patent Rights for the prevention and treatment of head and neck cancers. Upon the expiration or termination of the exclusive evaluation option license, Rapamycin Holdings, Inc. will have the exclusive right to execute an exclusive commercialization license which will supersede and replace the exclusive evaluation option license with no greater field of use and territory than granted in the exclusive evaluation option license.","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"National Institutes of Health","name":"National Institutes of Health","id":353,"url":"https://www.federalregister.gov/agencies/national-institutes-of-health","json_url":"https://www.federalregister.gov/api/v1/agencies/353","parent_id":221,"slug":"national-institutes-of-health"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2012/10/30/2012-26606.html","cfr_references":[],"citation":"77 FR 65699","comment_url":null,"comments_close_on":"2012-11-14","correction_of":null,"corrections":[],"dates":"Only written comments and/or applications for a license which are received by the NIH Office of Technology Transfer on or before November 14, 2012 will be considered.","disposition_notes":null,"docket_ids":[],"dockets":[],"document_number":"2012-26606","effective_on":null,"end_page":65700,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2012/10/30/2012-26606.xml","html_url":"https://www.federalregister.gov/documents/2012/10/30/2012-26606/prospective-grant-of-exclusive-license-development-of-chemopreventive-treatments-for-head-and-neck","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2012-26606?publication_date=2012-10-30","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2012-10-30/2012-26606/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":45,"last_updated":"2026-09-20 16:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2012-10-30/pdf/2012-26606.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2012-26606.pdf?1351516535","publication_date":"2012-10-30","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2012/10/30/2012-26606.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=NIH_FRDOC_0001","supporting_documents_count":0,"docket_id":"NIH_FRDOC_0001","regulation_id_number":null,"title":"Recently Posted NIH Rules and Notices.","checked_regulationsdotgov_at":"2012-11-19T06:00:12Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":65699,"subtype":null,"title":"Prospective Grant of Exclusive License: Development of Chemopreventive Treatments for Head and Neck Squamous Cell Carcinoma","toc_doc":"Development of Chemopreventive Treatments for Head and Neck Squamous Cell Carcinoma","toc_subject":"Prospective Grants of Exclusive Licenses:","topics":[],"type":"Notice","volume":77}