{"abstract":"This is notice, in accordance with 35 U.S.C. 209(c)(1) and 37 CFR 404.7(a)(1)(i), that the National Institutes of Health (NIH), Department of Health and Human Services (HHS), is contemplating the grant of a worldwide exclusive patent license, to practice the inventions embodied in PCT patent application PCT/US2012/044421, filed June 27, 2012 (HHS Reference<greek-i> E-205-2010/2-PCT-01), which is a continuation-in-part of U.S. Application No. 13/180,111 (E-205-2010/1- US-01) which claims priority to U.S. provisional application No. 61/ 363,079 (E-205-2010/0-US-01), and entitled \"Photosensitizing Antibody- Fluorophore Conjugates,\" to Aspyrian Therapeutics, Inc., a company incorporated under the laws of the State of Delaware, having its headquarters in San Diego, California. The United States of America is the assignee of the rights of the above invention. The field of use may be limited to \"use of photosensitizing antibody-fluorophore conjugate by itself for Photoimmunotherapy (PIT), or in combination with cancer therapeutic agents, to treat cancer or pre-cancerous hyperplasia\", and may be further limited to certain types of cancer and/or specific platforms. The license will include the priority case US 13/180,111, which is currently licensed to Aspyrian under an exclusive evaluation option license. The exclusive commercialization license proposed in this notice will supersede and replace the exclusive evaluation option license.","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"National Institutes of Health","name":"National Institutes of Health","id":353,"url":"https://www.federalregister.gov/agencies/national-institutes-of-health","json_url":"https://www.federalregister.gov/api/v1/agencies/353","parent_id":221,"slug":"national-institutes-of-health"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2013/03/28/2013-07166.html","cfr_references":[],"citation":"78 FR 18999","comment_url":null,"comments_close_on":"2013-04-12","correction_of":null,"corrections":[],"dates":"Only written comments and/or applications for a license received by the NIH Office of Technology Transfer on or before April 12, 2013 will be considered.","disposition_notes":null,"docket_ids":[],"dockets":[],"document_number":"2013-07166","effective_on":null,"end_page":18999,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2013/03/28/2013-07166.xml","html_url":"https://www.federalregister.gov/documents/2013/03/28/2013-07166/prospective-grant-of-start-up-exclusive-license-photosensitizing-antibody-fluorophore-conjugates-for","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2013-07166?publication_date=2013-03-28","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2013-03-28/2013-07166/mods.xml","not_received_for_publication":null,"page_length":1,"page_views":{"count":106,"last_updated":"2026-09-21 20:15:12 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2013-03-28/pdf/2013-07166.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2013-07166.pdf?1364388728","publication_date":"2013-03-28","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2013/03/28/2013-07166.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=NIH_FRDOC_0001","supporting_documents_count":0,"docket_id":"NIH_FRDOC_0001","regulation_id_number":null,"title":"Recently Posted NIH Rules and Notices.","checked_regulationsdotgov_at":"2013-04-17T08:07:09Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":18999,"subtype":null,"title":"Prospective Grant of Start-Up Exclusive License: Photosensitizing Antibody-Fluorophore Conjugates for Photoimmunotherapy","toc_doc":"Photosensitizing AntibodyFluorophore Conjugates for Photoimmunotherapy","toc_subject":"Prospective Grants of Start-Up Exclusive Licenses:","topics":[],"type":"Notice","volume":78}