{"abstract":"The Environmental Protection Agency (EPA) is announcing the availability of a final document titled, ``Integrated Science Assessment for Oxides of Nitrogen--Health Criteria'' (EPA/600/R-15/ 068). The document was prepared by the National Center for Environmental Assessment National Center for Environmental Assessment (NCEA) within the EPA's Office of Research and Development (ORD) as part of the review of the primary (health-based) National Ambient Air Quality Standards (NAAQS) for nitrogen dioxide (NO<INF>2</INF>). The Integrated Science Assessment (ISA), in conjunction with additional technical and policy assessments, provides the scientific basis for decisions by the EPA on the adequacy of the current NAAQS and the appropriateness of possible alternative standards. The EPA is developing a separate ISA and conducting a separate review for the secondary (welfare-based) NAAQS for NO<INF>2</INF>, in conjunction with a review of the secondary NAAQS for sulfur dioxide.","action":"Notice of availability.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2016/01/28/2016-01548.html","cfr_references":[],"citation":"81 FR 4910","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"The document will be available on or around January 28, 2016.","disposition_notes":null,"docket_ids":["Docket ID No. EPA-HQ-ORD-2013-0232","FRL-9941-74-ORD"],"dockets":[],"document_number":"2016-01548","effective_on":null,"end_page":4911,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2016/01/28/2016-01548.xml","html_url":"https://www.federalregister.gov/documents/2016/01/28/2016-01548/integrated-science-assessment-for-oxides-of-nitrogen-health-criteria","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2016-01548?publication_date=2016-01-28","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2016-01-28/2016-01548/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":1491,"last_updated":"2026-10-22 14:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2016-01-28/pdf/2016-01548.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2016-01548.pdf?1453902321","publication_date":"2016-01-28","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2016/01/28/2016-01548.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Final Integrated Science Assessment for Oxides of Nitrogen - Health Criteria - January 2016 [EPA/600/R-15/068]","document_id":"EPA-HQ-ORD-2013-0232-0046"},{"title":"Data Clarification Email between Drs. Meng, Kan, and Sacks","document_id":"EPA-HQ-ORD-2013-0232-0044"},{"title":"Second External Review Draft: Integrated Science Assessment for Oxide of Nitrogen - January 2015 [EPA/600/R-14/006]","document_id":"EPA-HQ-ORD-2013-0232-0036"},{"title":"Email from Dr. Lepeule to Dr. Patel; Answer to Data Request","document_id":"EPA-HQ-ORD-2013-0232-0033"},{"title":"Email from Dr. Brûske to Dr. Patel: Answer to Data Request","document_id":"EPA-HQ-ORD-2013-0232-0032"},{"title":"First External Review Draft of Integrated Science Assessment for Oxides of Nitrogen - Health Criteria [EPA/600/R-13/202]","document_id":"EPA-HQ-ORD-2013-0232-0023"},{"title":"Response to Data Request (Email from Dr. Strickland to Dr. Patel)","document_id":"EPA-HQ-ORD-2013-0232-0021"},{"title":"Email from Dr. Mulholland to Dr Richmond-Bryant; Response to Data Request","document_id":"EPA-HQ-ORD-2013-0232-0020"},{"title":"Email from Gretchen Tanner Goldman to Dr Richmond-Bryant; Response to Data Request","document_id":"EPA-HQ-ORD-2013-0232-0019"},{"title":"Email from Dr. Physick to Dr. Richmond-Bryant, Jennifer; Response to Data Request","document_id":"EPA-HQ-ORD-2013-0232-0018"}],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-ORD-2013-0232","supporting_documents_count":23,"docket_id":"EPA-HQ-ORD-2013-0232","regulation_id_number":null,"title":"Integrated Science Assessment for Oxides of Nitrogen - Health Criteria","checked_regulationsdotgov_at":"2016-02-17T06:00:13Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":4910,"subtype":null,"title":"Integrated Science Assessment for Oxides of Nitrogen-Health Criteria","toc_doc":"Integrated Science Assessment for Oxides of NitrogenHealth Criteria","toc_subject":null,"topics":[],"type":"Notice","volume":81}