{"abstract":"The Drug Enforcement Administration is placing the substance brivaracetam ((2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl] butanamide) (also referred to as BRV; UCB-34714; Briviact) (including its salts) into schedule V of the Controlled Substances Act. This scheduling action is pursuant to the Controlled Substances Act, as revised by the Improving Regulatory Transparency for New Medical Therapies Act which was signed into law on November 25, 2015.","action":"Interim final rule, with request for comments.","agencies":[{"raw_name":"DEPARTMENT OF JUSTICE","name":"Justice Department","id":268,"url":"https://www.federalregister.gov/agencies/justice-department","json_url":"https://www.federalregister.gov/api/v1/agencies/268","parent_id":null,"slug":"justice-department"},{"raw_name":"Drug Enforcement Administration","name":"Drug Enforcement Administration","id":116,"url":"https://www.federalregister.gov/agencies/drug-enforcement-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/116","parent_id":268,"slug":"drug-enforcement-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2016/05/12/2016-11245.html","cfr_references":[{"chapter":null,"citation_url":null,"part":1308,"title":21}],"citation":"81 FR 29487","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"The effective date of this rulemaking is May 12, 2016. Interested persons may file written comments on this rulemaking in accordance with 21 CFR 1308.43(g). Electronic comments must be submitted, and written comments must be postmarked, on or before June 13, 2016. Commenters should be aware that the electronic Federal Docket Management System will not accept comments after 11:59 p.m. Eastern Time on the last day of the comment period.","disposition_notes":null,"docket_ids":["Docket No. DEA-435"],"dockets":[],"document_number":"2016-11245","effective_on":"2016-05-12","end_page":29492,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2016/05/12/2016-11245.xml","html_url":"https://www.federalregister.gov/documents/2016/05/12/2016-11245/schedules-of-controlled-substances-placement-of-brivaracetam-into-schedule-v","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2016-11245?publication_date=2016-05-12","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2016-05-12/2016-11245/mods.xml","not_received_for_publication":null,"page_length":6,"page_views":{"count":3771,"last_updated":"2026-04-04 14:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2016-05-12/pdf/2016-11245.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2016-11245.pdf?1462970800","publication_date":"2016-05-12","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2016/05/12/2016-11245.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"DEA Background Data and Analysis_Brivaracetam_Dec2015","document_id":"DEA-2016-0008-0003"},{"title":"DEA 435_brivaracetam_HHS 09 08 2015","document_id":"DEA-2016-0008-0002"}],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=DEA-2016-0008","supporting_documents_count":2,"docket_id":"DEA-2016-0008","regulation_id_number":null,"title":"Schedules of Controlled Substances: Placement of Brivaracetam Into Schedule V","checked_regulationsdotgov_at":"2016-06-14T05:01:24Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":29487,"subtype":null,"title":"Schedules of Controlled Substances: Placement of Brivaracetam Into Schedule V","toc_doc":"Placement of Brivaracetam into Schedule V","toc_subject":"Schedules of Controlled Substances:","topics":["Administrative practice and procedure","Drug traffic control","Reporting and recordkeeping requirements"],"type":"Rule","volume":81}