{"abstract":"The Food and Drug Administration (FDA, we, the Agency) is amending the regulations for food additives permitted in feed and drinking water of animals to provide for the safe use of guanidinoacetic acid as a substance that spares arginine and serves as a precursor of creatine in broiler chicken and turkey feeds. This action is in response to a food additive petition filed by Alzchem AG.","action":"Final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2016/11/30/2016-28754.html","cfr_references":[{"chapter":null,"citation_url":null,"part":573,"title":21}],"citation":"81 FR 86268","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective November 30, 2016. Submit either written or electronic objections and requests for a hearing by December 30, 2016. See section V of this document for information on the filing of objections.","disposition_notes":null,"docket_ids":["Docket No. FDA-2015-F-2337"],"dockets":[],"document_number":"2016-28754","effective_on":"2016-11-30","end_page":86270,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2016/11/30/2016-28754.xml","html_url":"https://www.federalregister.gov/documents/2016/11/30/2016-28754/food-additives-permitted-in-feed-and-drinking-water-of-animals-guanidinoacetic-acid","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2016-28754?publication_date=2016-11-30","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2016-11-30/2016-28754/mods.xml","not_received_for_publication":null,"page_length":3,"page_views":{"count":728,"last_updated":"2026-08-26 20:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2016-11-30/pdf/2016-28754.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2016-28754.pdf?1480427219","publication_date":"2016-11-30","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2016/11/30/2016-28754.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=FDA-2015-F-2337","supporting_documents_count":0,"docket_id":"FDA-2015-F-2337","regulation_id_number":null,"title":"Alzchem AG; Filing of Food Additive Petition Animal Use","checked_regulationsdotgov_at":"2016-12-31T05:01:30Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":86268,"subtype":null,"title":"Food Additives Permitted in Feed and Drinking Water of Animals; Guanidinoacetic Acid","toc_doc":"Permitted in Feed and Drinking Water of Animals; Guanidinoacetic Acid","toc_subject":"Food Additives:","topics":["Food additives"],"type":"Rule","volume":81}