{"abstract":"The Food and Drug Administration (FDA, the Agency, or we) is amending the food additive regulations to no longer provide for the use of styrene as a flavoring substance and adjuvant for use in food because these uses have been abandoned. We are taking this action in response to a food additive petition submitted by the Styrene Information and Research Center (SIRC).","action":"Final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2018/10/09/2018-21808.html","cfr_references":[{"chapter":null,"citation_url":null,"part":172,"title":21}],"citation":"83 FR 50487","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective October 9, 2018. See section VIII for further information on the filing of objections. Submit either electronic or written objections and requests for a hearing on the final rule by November 8, 2018.","disposition_notes":null,"docket_ids":["Docket No. FDA-2016-F-1444"],"dockets":[],"document_number":"2018-21808","effective_on":"2018-10-09","end_page":50490,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2018/10/09/2018-21808.xml","html_url":"https://www.federalregister.gov/documents/2018/10/09/2018-21808/food-additives-permitted-for-direct-addition-to-food-for-human-consumption-styrene","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2018-21808?publication_date=2018-10-09","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2018-10-09/2018-21808/mods.xml","not_received_for_publication":null,"page_length":4,"page_views":{"count":1437,"last_updated":"2026-08-25 12:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2018-10-09/pdf/2018-21808.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2018-21808.pdf?1538743528","publication_date":"2018-10-09","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2018/10/09/2018-21808.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[],"comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=FDA-2016-F-1444","supporting_documents_count":0,"docket_id":"FDA-2016-F-1444","regulation_id_number":null,"title":"Styrene Information and Research Center; Filing of Food Additive Petition","checked_regulationsdotgov_at":"2018-12-01T17:01:15Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":50487,"subtype":null,"title":"Food Additives Permitted for Direct Addition to Food for Human Consumption; Styrene","toc_doc":"Styrene","toc_subject":"Food Additives Permitted for Direct Addition to Food for Human Consumption:","topics":["Food additives","Reporting and recordkeeping requirements"],"type":"Rule","volume":83}