{"abstract":"The Agency for Toxic Substances and Disease Registry (ATSDR), within the Department of Health and Human Services (HHS), announces the opening of a docket to obtain comments on Draft Toxicological Profiles for Dinitrophenols, 2-Butanone, Mirex and Chlordecone, 1,2- Diphenylhydrazine, 1,2,3-Trichloropropane, Lead, and Endrin. ATSDR has updated these profiles based on availability of new health effects information since their initial release. On March 21, 2016 ATSDR announced that it was preparing to develop Draft Toxicological Profiles for public comment release (81 FR 15110), which include those profiles mentioned above. All toxicological profiles issued as \"Drafts for Public Comment\" represent the result of ATSDR's evidence-based evaluations to provide important toxicological information on priority hazardous substances. ATSDR is seeking public comments and additional information or reports on studies about the health effects of dinitrophenols, 2-butanone, mirex and chlordecone, 1,2- diphenylhydrazine, 1,2,3-trichloropropane, lead, and endrin for review and potential inclusion in the profiles. ATSDR considers key studies for these substances during the profile development process. This document solicits any relevant, additional studies. ATSDR will evaluate the quality and relevance of such data or studies for possible inclusion into the profile.","action":"Notice with comment period.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Agency for Toxic Substances and Disease Registry","name":"Agency for Toxic Substances and Disease Registry","id":7,"url":"https://www.federalregister.gov/agencies/agency-for-toxic-substances-and-disease-registry","json_url":"https://www.federalregister.gov/api/v1/agencies/7","parent_id":221,"slug":"agency-for-toxic-substances-and-disease-registry"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2019/05/09/2019-09538.html","cfr_references":[],"citation":"84 FR 20359","comment_url":null,"comments_close_on":"2019-08-07","correction_of":null,"corrections":[],"dates":"Written comments must be received on or before August 7, 2019.","disposition_notes":null,"docket_ids":["Docket No. ATSDR-2019-0006"],"dockets":[{"supporting_documents":[{"title":"Draft Toxicological Profile for 1,2,3-Trichloropropane","document_id":"ATSDR-2019-0006-0009"},{"title":"Draft Toxicological Profile for Mirex and Chlordecone","document_id":"ATSDR-2019-0006-0008"},{"title":"Draft Toxicological Profile for Lead","document_id":"ATSDR-2019-0006-0007"},{"title":"Draft Toxicological Profile for Endrin","document_id":"ATSDR-2019-0006-0006"},{"title":"Draft Toxicological Profile for Dinitrophenols","document_id":"ATSDR-2019-0006-0005"},{"title":"ATSDR found errors in the document and are replacing with a corrected version.","document_id":"ATSDR-2019-0006-0004"},{"title":"Draft Toxicological Profile for 1,2-Diphenylhydrazine","document_id":"ATSDR-2019-0006-0003"},{"title":"Draft Toxicological Profile for 2-Butanone","document_id":"ATSDR-2019-0006-0002"}],"agency_name":"ATSDR","documents":[{"comment_count":6,"comment_start_date":"2019-05-09","updated_at":"2023-02-28T14:19:13.696-05:00","comment_url":"https://www.regulations.gov/commenton/ATSDR-2019-0006-0001","allow_late_comments":null,"id":"ATSDR-2019-0006-0001","comment_end_date":"2019-08-08","regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":8,"id":"ATSDR-2019-0006","title":"Availability of Draft Toxicological Profiles"}],"document_number":"2019-09538","effective_on":null,"end_page":20360,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2019/05/09/2019-09538.xml","html_url":"https://www.federalregister.gov/documents/2019/05/09/2019-09538/availability-of-draft-toxicological-profiles","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2019-09538?publication_date=2019-05-09","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2019-05-09/2019-09538/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":223,"last_updated":"2026-10-23 14:15:06 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2019-05-09/pdf/2019-09538.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2019-09538.pdf?1557319522","publication_date":"2019-05-09","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2019/05/09/2019-09538.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Draft Toxicological Profile for 1,2,3-Trichloropropane","document_id":"ATSDR-2019-0006-0009"},{"title":"Draft Toxicological Profile for Mirex and Chlordecone","document_id":"ATSDR-2019-0006-0008"},{"title":"Draft Toxicological Profile for Lead","document_id":"ATSDR-2019-0006-0007"},{"title":"Draft Toxicological Profile for Endrin","document_id":"ATSDR-2019-0006-0006"},{"title":"Draft Toxicological Profile for Dinitrophenols","document_id":"ATSDR-2019-0006-0005"},{"title":"ATSDR found errors in the document and are replacing with a corrected version.","document_id":"ATSDR-2019-0006-0004"},{"title":"Draft Toxicological Profile for 1,2-Diphenylhydrazine","document_id":"ATSDR-2019-0006-0003"},{"title":"Draft Toxicological Profile for 2-Butanone","document_id":"ATSDR-2019-0006-0002"}],"comments_count":6,"agency_id":"ATSDR","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=ATSDR-2019-0006","supporting_documents_count":8,"docket_id":"ATSDR-2019-0006","document_id":"ATSDR-2019-0006-0001","regulation_id_number":null,"title":"Availability of Draft Toxicological Profiles","checked_regulationsdotgov_at":"2023-02-28T19:19:12Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":20359,"subtype":null,"title":"Availability of Draft Toxicological Profiles","toc_doc":"Draft Toxicological Profiles","toc_subject":null,"topics":[],"type":"Notice","volume":84}