{"abstract":"This regulation establishes a temporary exemption from the requirement of a tolerance for residues of Ledprona (CAS# 2433753-68-3) in or on potatoes when used in accordance with the terms of Experimental Use Permit (EUP) No. 94614-EUP-1. GreenLight Bioscience, Inc. submitted a petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA) for a temporary exemption from the requirement of a tolerance for residues of Ledprona on all raw agricultural products and food products. After reviewing the petition and supporting data, the Agency has limited the temporary tolerance exemption to residues of Ledprona on potatoes only. This regulation eliminates the need to establish a maximum permissible level for residues of Ledprona in or on potatoes. This temporary tolerance exemption expires on April 30, 2025.","action":"Final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2023/05/04/2023-09486.html","cfr_references":[{"chapter":null,"citation_url":null,"part":180,"title":40}],"citation":"88 FR 28427","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This regulation is effective May 4, 2023. Objections and requests for hearings must be received on or before July 3, 2023, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).","disposition_notes":null,"docket_ids":["EPA-HQ-OPP-2022-0932","FRL-10947-01-OCSPP"],"dockets":[{"supporting_documents":[{"title":"Environmental Risk Assessment for a FIFRA Section 5 Experimental Use Permit for the New Product GS2 Formulation (Calantha) Containing Ledprona\n(Leptinotarsa decemlineata (Colorado Potato Beetle CPB)-specific recombinant double-stranded interfering Oligonucleotide GS2) at 0.8%","document_id":"EPA-HQ-OPP-2022-0932-0005"},{"title":"Human Health and Product Characterization for the Experimental Use Permit Application for Calantha™, containing 0.8% of the new active ingredient\n“Ledprona” dsRNA for use on potatoes and associated petition to establish a temporary tolerance exemption","document_id":"EPA-HQ-OPP-2022-0932-0004"},{"title":"GreenLight Biosciences, Inc. Notice of Filing to establish a temporary exemption from the requirement of a tolerance for the biochemical pesticide","document_id":"EPA-HQ-OPP-2022-0932-0002"}],"agency_name":"EPA","documents":[{"comment_count":0,"comment_start_date":"2023-05-04","updated_at":"2023-07-04T00:01:14.532-04:00","comment_url":"https://www.regulations.gov/commenton/EPA-HQ-OPP-2022-0932-0003","allow_late_comments":null,"id":"EPA-HQ-OPP-2022-0932-0003","comment_end_date":"2023-07-04","regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":3,"id":"EPA-HQ-OPP-2022-0932","title":"Pesticide Temporary Tolerance Exemption: Ledprona (2G9024), Experimental Use Permit"}],"document_number":"2023-09486","effective_on":"2023-05-04","end_page":28430,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2023/05/04/2023-09486.xml","html_url":"https://www.federalregister.gov/documents/2023/05/04/2023-09486/ledprona-cas-2433753-68-3-for-use-in-or-on-potato-temporary-exemption-from-the-requirement-of-a","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2023-09486?publication_date=2023-05-04","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2023-05-04/2023-09486/mods.xml","not_received_for_publication":null,"page_length":4,"page_views":{"count":1272,"last_updated":"2026-04-04 14:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2023-05-04/pdf/2023-09486.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2023-09486.pdf?1683117937","publication_date":"2023-05-04","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2023/05/04/2023-09486.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Environmental Risk Assessment for a FIFRA Section 5 Experimental Use Permit for the New Product GS2 Formulation (Calantha) Containing Ledprona\n(Leptinotarsa decemlineata (Colorado Potato Beetle CPB)-specific recombinant double-stranded interfering Oligonucleotide GS2) at 0.8%","document_id":"EPA-HQ-OPP-2022-0932-0005"},{"title":"Human Health and Product Characterization for the Experimental Use Permit Application for Calantha™, containing 0.8% of the new active ingredient\n“Ledprona” dsRNA for use on potatoes and associated petition to establish a temporary tolerance exemption","document_id":"EPA-HQ-OPP-2022-0932-0004"},{"title":"GreenLight Biosciences, Inc. Notice of Filing to establish a temporary exemption from the requirement of a tolerance for the biochemical pesticide","document_id":"EPA-HQ-OPP-2022-0932-0002"}],"comments_count":0,"agency_id":"EPA","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPP-2022-0932","supporting_documents_count":3,"docket_id":"EPA-HQ-OPP-2022-0932","document_id":"EPA-HQ-OPP-2022-0932-0003","regulation_id_number":null,"title":"Pesticide Temporary Tolerance Exemption: Ledprona (2G9024), Experimental Use Permit","checked_regulationsdotgov_at":"2023-07-31T23:41:55Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":28427,"subtype":null,"title":"Ledprona (CAS# 2433753-68-3) for Use in or on Potato; Temporary Exemption From the Requirement of a Tolerance","toc_doc":"Ledprona (CAS 2433753683) for Use in or on Potato","toc_subject":"Pesticide Tolerance; Exemptions, Petitions, Revocations, etc.:\n","topics":["Administrative practice and procedure","Agricultural commodities","Environmental protection","Pesticides and pests","Reporting and recordkeeping requirements"],"type":"Rule","volume":88}