{"abstract":"EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification, made an appropriate determination regarding that notification, and taken such actions as required by that determination.","action":"Final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2025/11/04/2025-19773.html","cfr_references":[{"chapter":null,"citation_url":null,"part":"721","title":40}],"citation":"90 FR 49218","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective on January 5, 2026. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EDT) on November 18, 2025.","disposition_notes":null,"docket_ids":["EPA-HQ-OPPT-2024-0332","FRL-12563-02-OCSPP"],"dockets":[{"supporting_documents":[{"title":"P-23-0176, 0179 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0055"},{"title":"P-23-0126 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0053"},{"title":"P-23-0126 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0052"},{"title":"P-23-0042 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0045"},{"title":"P-23-0042 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0044"},{"title":"P-23-0038 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0042"},{"title":"P-22-0192 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0041"},{"title":"P-22-0167 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0039"},{"title":"P-22-0155 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0035"},{"title":"P-22-0154 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0032"}],"agency_name":"EPA","documents":[{"comment_count":null,"comment_start_date":null,"updated_at":"2025-11-04T08:55:37.716-05:00","comment_url":"https://www.regulations.gov/commenton/EPA-HQ-OPPT-2024-0332-0067","allow_late_comments":false,"id":"EPA-HQ-OPPT-2024-0332-0067","comment_end_date":null,"regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":60,"id":"EPA-HQ-OPPT-2024-0332","title":"Significant New Use Rules on Certain Chemical Substances (24-4.5e)"}],"document_number":"2025-19773","effective_on":"2026-01-05","end_page":49234,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2025/11/04/2025-19773.xml","html_url":"https://www.federalregister.gov/documents/2025/11/04/2025-19773/significant-new-use-rules-on-certain-chemical-substances-24-45e","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2025-19773?publication_date=2025-11-04","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2025-11-04/2025-19773/mods.xml","not_received_for_publication":null,"page_length":17,"page_views":{"count":3941,"last_updated":"2026-07-26 20:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2025-11-04/pdf/2025-19773.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2025-19773.pdf?1762177507","publication_date":"2025-11-04","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2025/11/04/2025-19773.txt","regulation_id_number_info":{"2070-AB27":{"issue":"201404","html_url":"https://www.federalregister.gov/regulations/2070-AB27/significant-new-use-rule-snur-chemical-specific-snurs-to-extend-provisions-of-section-5-e-orders","title":"Significant New Use Rule (SNUR); Chemical-Specific SNURs To Extend Provisions of Section 5(e) Orders","xml_url":"http://www.reginfo.gov/public/do/eAgendaViewRule?pubId=201404&RIN=2070-AB27&operation=OPERATION_EXPORT_XML","priority_category":"Routine and Frequent"}},"regulation_id_numbers":["2070-AB27"],"regulations_dot_gov_info":{"supporting_documents":[{"title":"P-23-0176, 0179 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0055"},{"title":"P-23-0126 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0053"},{"title":"P-23-0126 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0052"},{"title":"P-23-0042 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0045"},{"title":"P-23-0042 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0044"},{"title":"P-23-0038 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0042"},{"title":"P-22-0192 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0041"},{"title":"P-22-0167 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0039"},{"title":"P-22-0155 Supporting Documents","document_id":"EPA-HQ-OPPT-2024-0332-0035"},{"title":"P-22-0154 PMN Sanitized","document_id":"EPA-HQ-OPPT-2024-0332-0032"}],"regulatory_plan":{"html_url":"https://www.federalregister.gov/regulations/2070-AB27/significant-new-use-rule-snur-chemical-specific-snurs-to-extend-provisions-of-section-5-e-orders","title":"Significant New Use Rule (SNUR); Chemical-Specific SNURs To Extend Provisions of Section 5(e) Orders"},"comments_count":0,"agency_id":"EPA","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPPT-2024-0332","supporting_documents_count":60,"docket_id":"EPA-HQ-OPPT-2024-0332","document_id":"EPA-HQ-OPPT-2024-0332-0067","regulation_id_number":"2070-AB27","title":"Significant New Use Rules on Certain Chemical Substances (24-4.5e)","checked_regulationsdotgov_at":"2025-11-05T17:55:04Z"},"regulations_dot_gov_url":null,"significant":false,"signing_date":null,"start_page":49218,"subtype":null,"title":"Significant New Use Rules on Certain Chemical Substances (24-4.5e)","toc_doc":"Certain Chemical Substances (24-4.5e)","toc_subject":"Significant New Uses","topics":["Chemicals","Environmental protection","Hazardous substances","Reporting and recordkeeping requirements"],"type":"Rule","volume":90}