{"abstract":"This regulation establishes tolerances for residues of pyriofenone in or on apple; apple, wet pomace; berry, low growing, subgroup 13-07G (except cranberry); and cherry subgroup 12-12A. ISK Biosciences Corporation requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).","action":"Final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2026/01/14/2026-00628.html","cfr_references":[{"chapter":null,"citation_url":null,"part":"180","title":40}],"citation":"91 FR 1392","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This regulation is effective January 14, 2026. Objections and requests for hearings must be received on or before March 16, 2026, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of this document).","disposition_notes":null,"docket_ids":["EPA-HQ-OPP-2024-0239","FRL-13069-01-OCSPP"],"dockets":[{"supporting_documents":[{"title":"Pyriofenone: Response to a Public Comment on EPA’s Notice of Receipt of Application for Apples and Cherrys","document_id":"EPA-HQ-OPP-2024-0239-0019"},{"title":"Pyriofenone. Human Health Risk Assessment for the Petition of New Uses on Cherry Crop Subgroup 12-12A and Apple; and Petition to Amend Tolerance on Berry, Low Growing, Subgroup 13-07G, Except Cranberry","document_id":"EPA-HQ-OPP-2024-0239-0018"},{"title":"Pyriofenone: Drinking Water Exposure Assessment for Proposed Section 3 New Uses on Apple and Cherry (Crop Subgroup 12-12A)","document_id":"EPA-HQ-OPP-2024-0239-0017"},{"title":"Pyriofenone. Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for the Section 3 New Uses of Pyriofenone on Apple and Cherry Crop Subgroup 12-12A; and Request to Amend Tolerance on Berry, Low Growing, Subgroup 13-07G, Except Cranberry","document_id":"EPA-HQ-OPP-2024-0239-0016"},{"title":"Pyriofenone. Occupational and Residential Exposure Assessment for Proposed Use on Apple and Cherry Subgroup 12-12A","document_id":"EPA-HQ-OPP-2024-0239-0015"},{"title":"ISK Biosciences Corporation Notice of Filing Pesticide Petition by amending a tolerance for residues of the fungicide pyriofenone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone, including its metabolites and degradates, in or on the raw agricultural commodity Berry, low growing subgroup 13-07G (except cranberry)","document_id":"EPA-HQ-OPP-2024-0239-0013"},{"title":"ISK Biosciences Corporation Notice of Filing Pesticide Petition by establishing a tolerance for residues of the fungicide pyriofenone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone, including its metabolites and degradates, in or on the raw agricultural commodity Apple, at 0.30 parts per million","document_id":"EPA-HQ-OPP-2024-0239-0012"}],"agency_name":"EPA","documents":[{"comment_count":4,"comment_start_date":"2026-01-14","updated_at":"2026-03-17T00:10:14.605-04:00","comment_url":"https://www.regulations.gov/commenton/EPA-HQ-OPP-2024-0239-0014","allow_late_comments":false,"id":"EPA-HQ-OPP-2024-0239-0014","comment_end_date":"2026-03-17","regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":7,"id":"EPA-HQ-OPP-2024-0239","title":"Pyriofenone on Apple and Cherry subgroup 12-12A petiton# 4F9115 and Pyriofenone on berry subgroup 13-07G (except cranberry) petition #4F9119"}],"document_number":"2026-00628","effective_on":"2026-01-14","end_page":1396,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2026/01/14/2026-00628.xml","html_url":"https://www.federalregister.gov/documents/2026/01/14/2026-00628/pyriofenone-pesticide-tolerances","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2026-00628?publication_date=2026-01-14","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2026-01-14/2026-00628/mods.xml","not_received_for_publication":null,"page_length":5,"page_views":{"count":338,"last_updated":"2026-06-27 02:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2026-01-14/pdf/2026-00628.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2026-00628.pdf?1768311926","publication_date":"2026-01-14","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2026/01/14/2026-00628.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"Pyriofenone: Response to a Public Comment on EPA’s Notice of Receipt of Application for Apples and Cherrys","document_id":"EPA-HQ-OPP-2024-0239-0019"},{"title":"Pyriofenone. Human Health Risk Assessment for the Petition of New Uses on Cherry Crop Subgroup 12-12A and Apple; and Petition to Amend Tolerance on Berry, Low Growing, Subgroup 13-07G, Except Cranberry","document_id":"EPA-HQ-OPP-2024-0239-0018"},{"title":"Pyriofenone: Drinking Water Exposure Assessment for Proposed Section 3 New Uses on Apple and Cherry (Crop Subgroup 12-12A)","document_id":"EPA-HQ-OPP-2024-0239-0017"},{"title":"Pyriofenone. Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for the Section 3 New Uses of Pyriofenone on Apple and Cherry Crop Subgroup 12-12A; and Request to Amend Tolerance on Berry, Low Growing, Subgroup 13-07G, Except Cranberry","document_id":"EPA-HQ-OPP-2024-0239-0016"},{"title":"Pyriofenone. Occupational and Residential Exposure Assessment for Proposed Use on Apple and Cherry Subgroup 12-12A","document_id":"EPA-HQ-OPP-2024-0239-0015"},{"title":"ISK Biosciences Corporation Notice of Filing Pesticide Petition by amending a tolerance for residues of the fungicide pyriofenone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone, including its metabolites and degradates, in or on the raw agricultural commodity Berry, low growing subgroup 13-07G (except cranberry)","document_id":"EPA-HQ-OPP-2024-0239-0013"},{"title":"ISK Biosciences Corporation Notice of Filing Pesticide Petition by establishing a tolerance for residues of the fungicide pyriofenone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone, including its metabolites and degradates, in or on the raw agricultural commodity Apple, at 0.30 parts per million","document_id":"EPA-HQ-OPP-2024-0239-0012"}],"comments_count":4,"agency_id":"EPA","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPP-2024-0239","supporting_documents_count":7,"docket_id":"EPA-HQ-OPP-2024-0239","document_id":"EPA-HQ-OPP-2024-0239-0014","regulation_id_number":null,"title":"Pyriofenone on Apple and Cherry subgroup 12-12A petiton# 4F9115 and Pyriofenone on berry subgroup 13-07G (except cranberry) petition #4F9119","checked_regulationsdotgov_at":"2026-03-17T08:55:04Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":1392,"subtype":null,"title":"Pyriofenone; Pesticide Tolerances","toc_doc":"Pyriofenone","toc_subject":"Pesticide Tolerance; Exemptions, Petitions, Revocations, etc.","topics":["Administrative practice and procedure","Agricultural commodities","Environmental protection","Pesticides and pests","Reporting and recordkeeping requirements"],"type":"Rule","volume":91}