{"abstract":"The Environmental Protection Agency (EPA or Agency) is announcing the availability of the final risk evaluation under the Toxic Substances Control Act (TSCA) for 1,2-dichloroethane (CASRN 107- 06-2). The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA used the best available science to prepare this final risk evaluation and determined, based on the weight of scientific evidence, that 1,2-dichloroethane presents an unreasonable risk of injury to human health driven by risk to workers through workplace exposure under 15 COUs. EPA did not identify contributions to unreasonable risk of injury for consumer exposure, exposure to the general population, or to the environment, under any COUs for 1,2-dichlorethane. Consistent with TSCA, EPA will now initiate risk management actions to address the unreasonable risk.","action":"Notice.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2026/05/05/2026-08682.html","cfr_references":[],"citation":"91 FR 24230","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":null,"disposition_notes":null,"docket_ids":["EPA-HQ-OPPT-2018-0427","FRL-11809-05-OCSPP"],"dockets":[{"supporting_documents":[{"title":"59. Benchmark Dose Modeling for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0240"},{"title":"49. Supplemental Information on HEM NEI Exposure and Risk Analysis for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0230"},{"title":"26. Water Releases for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0207"},{"title":"13. Environmental Hazard Assessment for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0194"},{"title":"04. Byproducts Assessment for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0185"},{"title":"Vinyl Institute EDC Consortium Recommendations to EPA on Studies Improving the Scientific Quality of the EDC Risk Evaluation","document_id":"EPA-HQ-OPPT-2018-0427-0178"},{"title":"EPA Response to ACC on Public Comment Extension Request for 12DCA Draft Risk Evaluation","document_id":"EPA-HQ-OPPT-2018-0427-0167"},{"title":"63. OPPT/ECRAD Review of OECD 428 Report Submission to EPA Test Order for 1,1-Dichloroethane (CAS No 75-34-3)","document_id":"EPA-HQ-OPPT-2018-0427-0134"},{"title":"61. Risk Evaluation for 1,1-Dichloroethane – Supplemental Information File: in vitro Dermal Absorption Study Analysis","document_id":"EPA-HQ-OPPT-2018-0427-0132"},{"title":"59. OPPT/ECRAD Review of OECD 428 Report Submission to EPA Test Order for 1,2-Dichloroethane (CAS No 107-06-2)","document_id":"EPA-HQ-OPPT-2018-0427-0130"}],"agency_name":"EPA","documents":[{"comment_count":null,"comment_start_date":null,"updated_at":"2026-05-05T11:59:22.921-04:00","comment_url":"https://www.regulations.gov/commenton/EPA-HQ-OPPT-2018-0427-0182","allow_late_comments":false,"id":"EPA-HQ-OPPT-2018-0427-0182","comment_end_date":null,"regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":170,"id":"EPA-HQ-OPPT-2018-0427","title":"1,2-Dichloroethane; TSCA Review"}],"document_number":"2026-08682","effective_on":null,"end_page":24231,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2026/05/05/2026-08682.xml","html_url":"https://www.federalregister.gov/documents/2026/05/05/2026-08682/12-dichloroethane-final-risk-evaluation-under-the-toxic-substances-control-act-tsca-notice-of","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2026-08682?publication_date=2026-05-05","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2026-05-05/2026-08682/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":743,"last_updated":"2026-07-27 08:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2026-05-05/pdf/2026-08682.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2026-08682.pdf?1777898749","publication_date":"2026-05-05","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2026/05/05/2026-08682.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"59. Benchmark Dose Modeling for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0240"},{"title":"49. Supplemental Information on HEM NEI Exposure and Risk Analysis for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0230"},{"title":"26. Water Releases for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0207"},{"title":"13. Environmental Hazard Assessment for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0194"},{"title":"04. Byproducts Assessment for 1,2-Dichloroethane","document_id":"EPA-HQ-OPPT-2018-0427-0185"},{"title":"Vinyl Institute EDC Consortium Recommendations to EPA on Studies Improving the Scientific Quality of the EDC Risk Evaluation","document_id":"EPA-HQ-OPPT-2018-0427-0178"},{"title":"EPA Response to ACC on Public Comment Extension Request for 12DCA Draft Risk Evaluation","document_id":"EPA-HQ-OPPT-2018-0427-0167"},{"title":"63. OPPT/ECRAD Review of OECD 428 Report Submission to EPA Test Order for 1,1-Dichloroethane (CAS No 75-34-3)","document_id":"EPA-HQ-OPPT-2018-0427-0134"},{"title":"61. Risk Evaluation for 1,1-Dichloroethane – Supplemental Information File: in vitro Dermal Absorption Study Analysis","document_id":"EPA-HQ-OPPT-2018-0427-0132"},{"title":"59. OPPT/ECRAD Review of OECD 428 Report Submission to EPA Test Order for 1,2-Dichloroethane (CAS No 107-06-2)","document_id":"EPA-HQ-OPPT-2018-0427-0130"}],"comments_count":0,"agency_id":"EPA","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPPT-2018-0427","supporting_documents_count":169,"docket_id":"EPA-HQ-OPPT-2018-0427","document_id":"EPA-HQ-OPPT-2018-0427-0182","regulation_id_number":null,"title":"1,2-Dichloroethane; TSCA Review","checked_regulationsdotgov_at":"2026-05-06T11:55:08Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":24230,"subtype":null,"title":"1,2-Dichloroethane; Final Risk Evaluation Under the Toxic Substances Control Act (TSCA); Notice of Availability","toc_doc":"1,2-Dichloroethane","toc_subject":"Risk Evaluation under the Toxic Substances Control Act","topics":[],"type":"Notice","volume":91}