{"abstract":"Clinical laboratory testing technology has advanced significantly since the Clinical Laboratory Improvement Amendments of 1988 (CLIA) regulations were implemented in 1992. This request for information (RFI) seeks input from the public regarding various topics related to the CLIA regulations, including: breath testing; laboratory processes and procedures; emergency preparedness, biosafety and biosecurity, and cybersecurity; and specialty testing areas. Responses to this RFI may be used to help inform CMS and the CDC as to what types of action, if any, should be taken to update the existing CLIA regulations through future notice and comment rulemaking.","action":"Request for information.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Centers for Medicare & Medicaid Services","name":"Centers for Medicare & Medicaid Services","id":45,"url":"https://www.federalregister.gov/agencies/centers-for-medicare-medicaid-services","json_url":"https://www.federalregister.gov/api/v1/agencies/45","parent_id":221,"slug":"centers-for-medicare-medicaid-services"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2026/07/16/2026-14358.html","cfr_references":[{"chapter":null,"citation_url":null,"part":"493","title":42}],"citation":"91 FR 43586","comment_url":null,"comments_close_on":"2026-09-14","correction_of":null,"corrections":[],"dates":"To be assured consideration, comments must be received at one of the addresses provided below, by September 14, 2026.","disposition_notes":null,"docket_ids":["CMS-3485-NC"],"dockets":[{"supporting_documents":[],"agency_name":"CMS","documents":[{"comment_count":374,"comment_start_date":"2026-07-16","updated_at":"2026-09-16T01:56:49.260-04:00","comment_url":"https://www.regulations.gov/commenton/CMS-2026-2345-0001","allow_late_comments":false,"id":"CMS-2026-2345-0001","comment_end_date":"2026-09-15","regulations_dot_gov_open_for_comment":false}],"supporting_documents_count":0,"id":"CMS-2026-2345","title":"Request for Information; Clinical Laboratory Improvement Amendments (CLIA) of 1988 Regulations.  CMS-3485-NC"}],"document_number":"2026-14358","effective_on":null,"end_page":43591,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2026/07/16/2026-14358.xml","html_url":"https://www.federalregister.gov/documents/2026/07/16/2026-14358/request-for-information-clinical-laboratory-improvement-amendments-of-1988-clia-regulations","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2026-14358?publication_date=2026-07-16","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2026-07-16/2026-14358/mods.xml","not_received_for_publication":null,"page_length":6,"page_views":{"count":16426,"last_updated":"2026-09-21 04:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2026-07-16/pdf/2026-14358.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2026-14358.pdf?1784119523","publication_date":"2026-07-16","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2026/07/16/2026-14358.txt","regulation_id_number_info":{"0938-AW01":null},"regulation_id_numbers":["0938-AW01"],"regulations_dot_gov_info":{"supporting_documents":[],"comments_count":374,"agency_id":"CMS","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=CMS-2026-2345","supporting_documents_count":0,"docket_id":"CMS-2026-2345","document_id":"CMS-2026-2345-0001","regulation_id_number":"0938-AW01","title":"Request for Information; Clinical Laboratory Improvement Amendments (CLIA) of 1988 Regulations.  CMS-3485-NC","checked_regulationsdotgov_at":"2026-09-17T08:55:03Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":43586,"subtype":null,"title":"Request for Information; Clinical Laboratory Improvement Amendments of 1988 (CLIA) Regulations","toc_doc":"Clinical Laboratory Improvement Amendments of 1988 Regulations","toc_subject":"Request for Information","topics":[],"type":"Proposed Rule","volume":91}