{"abstract":"This regulation establishes exemptions from the requirement of a tolerance for residues of dimethyl sulfoxide (CAS Reg. No. 67-68-5) when used as an inert ingredient (solvent/cosolvent) in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest, in pesticide formulations applied to animals, and in antimicrobial formulations applied to food-contact surfaces in public eating places, dairy-processing equipment, and food- processing equipment and utensils. Spring Regulatory Sciences on behalf of Gaylord Chemical Company, LLC submitted a petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting establishment of exemptions from the requirement of a tolerance. This regulation eliminates the need to establish maximum permissible levels for residues of dimethyl sulfoxide when used in accordance with the terms of those exemptions.","action":"Final rule.","agencies":[{"raw_name":"ENVIRONMENTAL PROTECTION AGENCY","name":"Environmental Protection Agency","id":145,"url":"https://www.federalregister.gov/agencies/environmental-protection-agency","json_url":"https://www.federalregister.gov/api/v1/agencies/145","parent_id":null,"slug":"environmental-protection-agency"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2026/10/30/2026-22176.html","cfr_references":[{"chapter":null,"citation_url":null,"part":"180","title":40}],"citation":"91 FR 68480","comment_url":"http://www.regulations.gov/commenton/EPA-HQ-OPP-2026-0529-0006","comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This regulation is effective October 30, 2026. Objections and requests for hearings must be received on or before December 29, 2026 and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of this document).","disposition_notes":null,"docket_ids":["EPA-HQ-OPP-2026-0529","FRL-13642-01-OCSPP"],"dockets":[{"supporting_documents":[{"title":"IN-12546; Dimethyl Sulfoxide. Human Health Risk Assessment and Ecological Effects Assessment to Support Inert Ingredient Approval for use in Pesticide Formulations","document_id":"EPA-HQ-OPP-2026-0529-0007"},{"title":"Gaylord Chemical Company, L.L.C Notice of Filing Pesticide Petition to allow the use as an inert ingredient solvent or co-solvent in pesticide formulations applied to growing cropspre- and post-harvest, applied to animals, and in antimicrobial pesticide formulations applied to Food-contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils","document_id":"EPA-HQ-OPP-2026-0529-0002"}],"agency_name":"EPA","documents":[{"comment_count":0,"comment_start_date":"2026-10-30","updated_at":"2026-10-30T11:56:41.978-04:00","comment_url":"https://www.regulations.gov/commenton/EPA-HQ-OPP-2026-0529-0006","allow_late_comments":false,"id":"EPA-HQ-OPP-2026-0529-0006","comment_end_date":"2026-12-30","regulations_dot_gov_open_for_comment":true}],"supporting_documents_count":2,"id":"EPA-HQ-OPP-2026-0529","title":"IN-12546; Dimethyl Sulfoxide"}],"document_number":"2026-22176","effective_on":"2026-10-30","end_page":68484,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2026/10/30/2026-22176.xml","html_url":"https://www.federalregister.gov/documents/2026/10/30/2026-22176/dimethyl-sulfoxide-in-pesticide-formulations-exemptions-from-the-requirement-of-a-tolerance","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/2026-22176?publication_date=2026-10-30","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2026-10-30/2026-22176/mods.xml","not_received_for_publication":null,"page_length":5,"page_views":{"count":149,"last_updated":"2026-11-02 02:15:03 -0500"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2026-10-30/pdf/2026-22176.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":"https://public-inspection.federalregister.gov/2026-22176.pdf?1793277914","publication_date":"2026-10-30","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2026/10/30/2026-22176.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"supporting_documents":[{"title":"IN-12546; Dimethyl Sulfoxide. Human Health Risk Assessment and Ecological Effects Assessment to Support Inert Ingredient Approval for use in Pesticide Formulations","document_id":"EPA-HQ-OPP-2026-0529-0007"},{"title":"Gaylord Chemical Company, L.L.C Notice of Filing Pesticide Petition to allow the use as an inert ingredient solvent or co-solvent in pesticide formulations applied to growing cropspre- and post-harvest, applied to animals, and in antimicrobial pesticide formulations applied to Food-contact surfaces in public eating places, dairy-processing equipment, and food-processing equipment and utensils","document_id":"EPA-HQ-OPP-2026-0529-0002"}],"comments_count":0,"agency_id":"EPA","comments_url":"https://www.regulations.gov/docketBrowser?rpp=50&so=DESC&sb=postedDate&po=0&dct=PS&D=EPA-HQ-OPP-2026-0529","supporting_documents_count":2,"docket_id":"EPA-HQ-OPP-2026-0529","document_id":"EPA-HQ-OPP-2026-0529-0006","regulation_id_number":null,"title":"IN-12546; Dimethyl Sulfoxide","checked_regulationsdotgov_at":"2026-11-02T05:01:25Z"},"regulations_dot_gov_url":"http://www.regulations.gov/commenton/EPA-HQ-OPP-2026-0529-0006","significant":null,"signing_date":null,"start_page":68480,"subtype":null,"title":"Dimethyl Sulfoxide in Pesticide Formulations; Exemptions From the Requirement of a Tolerance","toc_doc":"Dimethyl Sulfoxide","toc_subject":"Pesticide Tolerance; Exemptions, Petitions, Revocations, etc.","topics":["Administrative practice and procedure","Agricultural commodities","Environmental protection","Pesticides and pests","Reporting and recordkeeping requirements"],"type":"Rule","volume":91}