{"abstract":"The Food and Drug Administration (FDA) is issuing a tentative final rule to amend its regulations to affirm that egg white lysozyme enzyme preparation, when labeled by the common or usual name ``egg white lysozyme'' to identify its source, is generally recognized as safe (GRAS) for use in preventing late blowing of cheese caused by the bacterium Clostridium tyrobutyricum during cheese production. This action is in response to a petition submitted by Fordras S.A. (formerly SPA-Societa Prodotti Antibiotici S.p.A.). FDA has tentatively concluded that this use of the egg white lysozyme enzyme preparation is GRAS only when the ingredient statement for both bulk and packaged food that contains cheese manufactured using egg white lysozyme includes the common or usual name ``egg white lysozyme'' to identify the source of the protein. To give interested persons an opportunity to comment on this condition of use required for GRAS status, FDA is issuing this tentative final rule.","action":"Tentative final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/1998/03/13/98-6571.html","cfr_references":[{"chapter":null,"citation_url":null,"part":184,"title":21}],"citation":"63 FR 12421","comment_url":null,"comments_close_on":"1998-05-27","correction_of":null,"corrections":[],"dates":"Submit written comments by May 27, 1998.","disposition_notes":null,"docket_ids":["Docket No. 89G-0393"],"dockets":[],"document_number":"98-6571","effective_on":null,"end_page":12426,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":null,"html_url":"https://www.federalregister.gov/documents/1998/03/13/98-6571/direct-food-substances-affirmed-as-generally-recognized-as-safe-egg-white-lysozyme","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/98-6571?publication_date=1998-03-13","mods_url":"https://www.govinfo.gov/metadata/granule/FR-1998-03-13/98-6571/mods.xml","not_received_for_publication":null,"page_length":6,"page_views":{"count":159,"last_updated":"2026-09-21 20:15:12 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-1998-03-13/pdf/98-6571.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"1998-03-13","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/1998/03/13/98-6571.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-09-21T01:48:33Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":12421,"subtype":null,"title":"Direct Food Substances Affirmed as Generally Recognized as Safe; Egg White Lysozyme","toc_doc":null,"toc_subject":null,"topics":[],"type":"Proposed Rule","volume":63}