{"abstract":"The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled ``Population Pharmacokinetics.'' This guidance provides recommendations to pharmaceutical industry scientists, who have long been interested in the application of population pharmacokinetics, during the new drug development, safety and efficacy evaluation, and approval processes.","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/1999/02/10/99-3156.html","cfr_references":[],"citation":"64 FR 6663","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"Written comments on the guidance may be submitted at any time. General comments on agency guidance documents are welcome at any time.","disposition_notes":null,"docket_ids":["Docket No. 97D-0383"],"dockets":[],"document_number":"99-3156","effective_on":null,"end_page":6664,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":null,"html_url":"https://www.federalregister.gov/documents/1999/02/10/99-3156/guidance-for-industry-on-population-pharmacokinetics-availability","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/99-3156?publication_date=1999-02-10","mods_url":"https://www.govinfo.gov/metadata/granule/FR-1999-02-10/99-3156/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":98,"last_updated":"2026-04-04 14:15:05 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-1999-02-10/pdf/99-3156.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"1999-02-10","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/1999/02/10/99-3156.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-09-21T00:14:26Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":6663,"subtype":null,"title":"Guidance for Industry on Population Pharmacokinetics; Availability","toc_doc":null,"toc_subject":null,"topics":[],"type":"Notice","volume":64}