{"abstract":"The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by Orion Corp. The supplemental NADA adds a claim for reversal of the sedative and analgesic effects of dexmedetomidine hydrochloride to labeling for atipamezole hydrochloride injectable solution for dogs.","action":"Final rule.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2007/01/04/E6-22515.html","cfr_references":[{"chapter":null,"citation_url":null,"part":522,"title":21}],"citation":"72 FR 264","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective January 4, 2007.","disposition_notes":null,"docket_ids":[],"dockets":[],"document_number":"E6-22515","effective_on":"2007-01-04","end_page":264,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2007/01/04/E6-22515.xml","html_url":"https://www.federalregister.gov/documents/2007/01/04/E6-22515/implantation-or-injectable-dosage-form-new-animal-drugs-atipamezole","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/E6-22515?publication_date=2007-01-04","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2007-01-04/E6-22515/mods.xml","not_received_for_publication":null,"page_length":1,"page_views":{"count":82,"last_updated":"2026-04-05 02:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2007-01-04/pdf/E6-22515.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2007-01-04","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2007/01/04/E6-22515.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-11-12T20:29:22Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":264,"subtype":null,"title":"Implantation or Injectable Dosage Form New Animal Drugs; Atipamezole","toc_doc":"Atipamezole","toc_subject":"Animal drugs, feeds, and related products:","topics":["Animal drugs"],"type":"Rule","volume":72}