{"abstract":"The Food and Drug Administration (FDA) is confirming the effective date of February 19, 2008, for the direct final rule that appeared in the Federal Register of August 16, 2007 (72 FR 45883). The direct final rule amends the biologics regulations by removing, revising, or updating specific regulations applicable to blood, blood components and Source Plasma to be more consistent with current practices in the blood industry and to remove unnecessary or outdated requirements. In addition, FDA is making technical amendments to the biologics regulations in response to comments received on the direct final rule.","action":"Direct final rule; confirmation of effective date and technical amendment.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2008/02/08/E8-2322.html","cfr_references":[{"chapter":null,"citation_url":null,"part":606,"title":21},{"chapter":null,"citation_url":null,"part":607,"title":21},{"chapter":null,"citation_url":null,"part":610,"title":21},{"chapter":null,"citation_url":null,"part":640,"title":21}],"citation":"73 FR 7463","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"The effective date for the regulation is confirmed as February 19, 2008. The effective date of the technical amendment is also February 19, 2008.","disposition_notes":null,"docket_ids":["Docket No. FDA-2008-N-0067"],"dockets":[],"document_number":"E8-2322","effective_on":"2008-02-19","end_page":7464,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2008/02/08/E8-2322.xml","html_url":"https://www.federalregister.gov/documents/2008/02/08/E8-2322/revisions-to-the-requirements-applicable-to-blood-blood-components-and-source-plasma-confirmation-of","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/E8-2322?publication_date=2008-02-08","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2008-02-08/E8-2322/mods.xml","not_received_for_publication":null,"page_length":2,"page_views":{"count":69,"last_updated":"2026-04-04 12:15:04 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2008-02-08/pdf/E8-2322.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2008-02-08","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2008/02/08/E8-2322.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-11-13T18:16:55Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":7463,"subtype":null,"title":"Revisions to the Requirements Applicable to Blood, Blood Components and Source Plasma; Confirmation of Effective Date and Technical Amendment","toc_doc":"Revisions to the Requirements Applicable to Blood, Blood Components and Source Plasma; Confirmation of Effective Date and Technical Amendment","toc_subject":null,"topics":[],"type":"Rule","volume":73}