{"abstract":"The Food and Drug Administration (FDA) is amending certain regulations regarding generally recognized as safe (GRAS) substances to remove references to FDA development of food-grade specifications in cooperation with the National Academy of Sciences (NAS, now the National Academies). This action is editorial in nature and is intended to ensure the accuracy of the agency's regulations.","action":"Final rule; technical amendments.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Food and Drug Administration","name":"Food and Drug Administration","id":199,"url":"https://www.federalregister.gov/agencies/food-and-drug-administration","json_url":"https://www.federalregister.gov/api/v1/agencies/199","parent_id":221,"slug":"food-and-drug-administration"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2008/02/14/E8-2809.html","cfr_references":[{"chapter":null,"citation_url":null,"part":184,"title":21}],"citation":"73 FR 8606","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"This rule is effective February 14, 2008.","disposition_notes":null,"docket_ids":["Docket No. FDA-2008-N-0068"],"dockets":[],"document_number":"E8-2809","effective_on":"2008-02-14","end_page":8608,"executive_order_notes":null,"executive_order_number":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2008/02/14/E8-2809.xml","html_url":"https://www.federalregister.gov/documents/2008/02/14/E8-2809/generally-recognized-as-safe-substances-technical-amendments","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/E8-2809?publication_date=2008-02-14","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2008-02-14/E8-2809/mods.xml","not_received_for_publication":null,"page_length":3,"page_views":{"count":414,"last_updated":"2026-07-28 16:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2008-02-14/pdf/E8-2809.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2008-02-14","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2008/02/14/E8-2809.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2011-11-13T19:09:42Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":8606,"subtype":null,"title":"Generally Recognized As Safe Substances; Technical Amendments","toc_doc":"Generally Recognized As Safe Substances; Technical Amendments","toc_subject":null,"topics":["Food additives"],"type":"Rule","volume":73}