{"abstract":"The National Health and Nutrition Examination Survey (NHANES) is a program of periodic surveys conducted by the National Center for Health Statistics (NCHS) of the Centers for Disease Control and Prevention (CDC). Examination surveys conducted since 1960 by NCHS have provided national estimates of the health and nutritional status of the U.S. civilian non-institutionalized population. To add to the extensive amount of information collected for the purpose of describing the health of the population, DNA specimens were collected during three NHANES surveys. DNA is available in the form of crude lysates of cell lines derived from approximately 7,157 participants enrolled in Phase II of NHANES III (1991-1994). In addition, DNA purified from whole blood is also available from approximately 7,900 participants enrolled in the NHANES 1999-2002 and 4,621 participants enrolled in NHANES 2007- 2008. All specimens (NHANES III, NHANES 1999-2002 and NHANES 2007-2008) were sent to the Division of Laboratory Sciences (DLS) at the National Center for Environmental Health (NCEH) for processing. DNA samples from these specimens are being made available to the research community for genetic analyses. No funding is provided as part of this solicitation. NCHS will review proposals twice a year beginning in January and July of each year. Proposals will be reviewed by a technical panel and by an internal Secondary Review Committee of senior CDC scientists. The Secondary Review Committee will perform a programmatic review based on the results of the technical review panel and consider the scientific and technical results from the first level of review, important programmatic considerations such as program priorities, program relevance, and other criteria germane to this announcement and to CDC. Projects approved by both reviews will be submitted to the NCHS Ethics Review Board for final approval. Approved projects that do not obtain funding on their own will be canceled. A more complete description of this program follows.","action":"Notice.","agencies":[{"raw_name":"DEPARTMENT OF HEALTH AND HUMAN SERVICES","name":"Health and Human Services Department","id":221,"url":"https://www.federalregister.gov/agencies/health-and-human-services-department","json_url":"https://www.federalregister.gov/api/v1/agencies/221","parent_id":null,"slug":"health-and-human-services-department"},{"raw_name":"Centers for Disease Control and Prevention","name":"Centers for Disease Control and Prevention","id":44,"url":"https://www.federalregister.gov/agencies/centers-for-disease-control-and-prevention","json_url":"https://www.federalregister.gov/api/v1/agencies/44","parent_id":221,"slug":"centers-for-disease-control-and-prevention"}],"body_html_url":"https://www.federalregister.gov/documents/full_text/html/2009/09/03/E9-21287.html","cfr_references":[],"citation":"74 FR 45644","comment_url":null,"comments_close_on":null,"correction_of":null,"corrections":[],"dates":"<bullet> Submission of Proposals: On January 1 and July 1 of each year;","disposition_notes":null,"docket_ids":[],"dockets":[],"document_number":"E9-21287","effective_on":null,"end_page":45648,"executive_order_notes":null,"executive_order_number":null,"explanation":null,"full_text_xml_url":"https://www.federalregister.gov/documents/full_text/xml/2009/09/03/E9-21287.xml","html_url":"https://www.federalregister.gov/documents/2009/09/03/E9-21287/national-health-and-nutrition-examination-survey-nhanes-dna-samples-guidelines-for-proposals-to-use","images":{},"images_metadata":{},"json_url":"https://www.federalregister.gov/api/v1/documents/E9-21287?publication_date=2009-09-03","mods_url":"https://www.govinfo.gov/metadata/granule/FR-2009-09-03/E9-21287/mods.xml","not_received_for_publication":null,"page_length":5,"page_views":{"count":214,"last_updated":"2026-04-05 02:15:03 -0400"},"pdf_url":"https://www.govinfo.gov/content/pkg/FR-2009-09-03/pdf/E9-21287.pdf","presidential_document_number":null,"proclamation_number":null,"public_inspection_pdf_url":null,"publication_date":"2009-09-03","raw_text_url":"https://www.federalregister.gov/documents/full_text/text/2009/09/03/E9-21287.txt","regulation_id_number_info":{},"regulation_id_numbers":[],"regulations_dot_gov_info":{"checked_regulationsdotgov_at":"2009-09-07T18:07:12Z"},"regulations_dot_gov_url":null,"significant":null,"signing_date":null,"start_page":45644,"subtype":null,"title":"National Health and Nutrition Examination Survey (NHANES) DNA Samples: Guidelines for Proposals To Use Samples and Cost Schedule","toc_doc":"Guidelines for Proposals to Use Samples and Cost Schedule","toc_subject":"National Health and Nutrition Examination Survey DNA Samples:","topics":[],"type":"Notice","volume":74}