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Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Concerning Encapsulated High-Concentration Lipid A Composition as Immunogenic Agents to Produce Human Antibodies to Prevent or Treat Gram Negative Bacterial Infections

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Information about this document as published in the Federal Register.

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Department of the Army, DoD.




In accordance with 37 CFR 404.6, announcement is made of the availability for licensing of U.S. Patent No. 5,888,519 entitled “Encapsulated High-Concentration Lipid A Composition as Immunogenic Agents to Produce Human Antibodies to Prevent of Treat Gram Negative Bacterial Infections” issued March 30, 1999. The United States Government as Start Printed Page 8011represented by the Secretary of the Army has rights in this invention.


Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, Frederick, Maryland 21702-5012.

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For patent issues, Ms. Elizabeth Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul Mele, Office of Research & Technology Assessment, (301) 619-6664. Both at telefax (301) 619-5034.

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This invention is directed to the production of antibodies against lipid A by using encapsulating slow-releasing delivery materials or devices containing concentrations of lipid A that are greater than could be given safely to humans in the absence of said materials or devices. The antibodies to lipid A can be used for binding the antibodies to the lipid A that are present in the lipopolysaccharide that coats the surface of the Gram-negative bacteria.

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Luz D. Ortiz,

Army Federal Register Liaison Officer.

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[FR Doc. 02-4179 Filed 2-20-02; 8:45 am]