Skip to Content


Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Application Concerning Chemosensitizing Agents Against Choroquine Resistant P. Falciparum and Methods of Making and Using Thereof

Document Details

Information about this document as published in the Federal Register.

Published Document

This document has been published in the Federal Register. Use the PDF linked in the document sidebar for the official electronic format.

Start Preamble


Department of the Army, DoD.




In accordance with 37 CFR 404.6 and 404.7, announcement is made of the availability for licensing of U.S. Patent Application No. 09/849,400 entitled “Chemosensitizing Agents Against Chloroquine Resistant P. Falciparum and Methods of Making and Using Thereof,” filed May 7, 2001. Foreign rights are also available (PCT/USO1/14574). The United States Government, as represented by the Secretary of the Army, has rights in this invention.


Commander, U.S. Army Medical Research and Materiel, Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, Frederick, MD 21702-5012.

Start Further Info


For patent issues, Ms. Elizabeth Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul Mele, Office of Research & Technology Assessment, (301) 610-6664, both at telefax (301) 619-5034.

End Further Info End Preamble Start Supplemental Information


A compound having the structural formula

or pharmaceutically acceptable salt or prodrug thereof, wherein X is a substituted or unsubstituted alkyl or a heteroatom; n is 4, 5 or 6; Y is a substituted or unsubsituted or alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, or

wherein R1 and R2 are each independently, H, a heteroatom, substituted or unsubstituted alkyl, cycloalkl, heterocycloalkyl, aryl, or heteroaryl; and wherein each ring structure are independently substituted or unsubsituted is disclosed. Also disclosed are chemosensitizing agents and methods of modulating, attenuating, reversing, or affecting a cell's or organism's resistance to a given drug such as an antimalarial.

Start Signature

Luz D. Ortiz,

Army Federal Register Liaison Officer.

End Signature End Supplemental Information

[FR Doc. 04-821 Filed 1-13-04; 8:45 am]