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National Toxicology Program (NTP); NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM); Availability of the Biennial Progress Report of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): NIH Publication No. 08-6529

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National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH).


Availability of the ICCVAM Biennial Progress Report.


NICEATM announces the availability of the “Biennial Progress Report: Interagency Coordinating Committee on the Validation of Alternative Methods: 2006-2007.” In accordance with requirements of the ICCVAM Authorization Act of 2000 (42 U.S.C. 285 l-3), this report describes progress and activities during 2006-2007 by ICCVAM and NICEATM. The report is available on the NICEATM-ICCVAM Web site at​about/​ICCVAMrpts.htm. Copies can also be requested from NICEATM at the address given below.


Requests for copies of the report should be sent by mail, fax, or email to Dr. William S. Stokes, NICEATM Director, NIEHS, P.O. Box 12233, MD EC-17, Research Triangle Park, NC 27709, (phone) 919-541-2384, (fax) 919-541-0947, (e-mail) Courier address: NICEATM, 79 T.W. Alexander Drive, Building 4401, Room 3128, Research Triangle Park, NC 27709.

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Dr. William S. Stokes, NICEATM Director (919-541-2384 or

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Background Information on ICCVAM, NICEATM, and SACATM

ICCVAM is an interagency committee composed of representatives from 15 Federal regulatory and research agencies that use, generate, or disseminate toxicological information. ICCVAM conducts technical evaluations of new, revised, and alternative methods with regulatory applicability. ICCVAM also promotes scientific validation, regulatory acceptance, and national and international harmonization of toxicological test methods that more accurately assess safety and hazards of chemicals and products and that refine, reduce, and replace animal use. The ICCVAM Authorization Act of 2000 (42 U.S.C. 285 l-3, available at​docs/​about_​docs/​PL106545.pdf) established ICCVAM as a permanent interagency committee of the NIEHS under NICEATM. NICEATM administers ICCVAM and provides scientific and operational support for ICCVAM-related activities. NICEATM and ICCVAM collaborate in evaluating new and improved test methods applicable to the needs of Federal agencies. Additional information about ICCVAM and NICEATM can be found at the NICEATM-ICCVAM Web site (

ICCVAM, NICEATM, and the Director of the NIEHS receive advice regarding statutorily mandated duties of ICCVAM and activities of NICEATM from the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM), a Federally chartered advisory committee. Additional information about SACATM, including the charter, roster, and records of past meetings, can be found at​go/​167.

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Dated: October 8, 2008.

Samuel H. Wilson,

Acting Director, National Institute of Environmental Health Sciences and National Toxicology Program.

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[FR Doc. E8-25223 Filed 10-22-08; 8:45 am]